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Meeting program

1st Global Meeting

Hilton Hotel, Liverpool, United Kingdom · 9–11 September 2022

Original program (meeting website)

About this meeting

Three days of keynote lectures, abstract presentations, and discussions led by the special interest groups. The program covered terminology, the experience of patients and families, the cerebellum's role in thinking and behavior, and new work in neuroradiology, neurosurgery, symptom scoring, ataxia, and rehabilitation. Each special interest group left with research priorities for the next global meeting.

Published proceedings: Walsh KS, Pizer B, Samargia-Grivette S, et al. Proceedings of the first global meeting of the Posterior Fossa Society: state of the art in cerebellar mutism syndrome. Childs Nerv Syst. 2024;40(7):2177–2191. Read it

Friday 9 September 2022

  1. 10:30–11:00

    Registration

  2. 11:00–11:10

    Welcome and introduction

    Barry Pizer and Karin Walsh

  3. 11:10–11:30

    The history of the Posterior Fossa Society

    Thora Gudrunardottir

  4. 11:30–12:00

    Patient impact

    Liz Hull

  5. 12:00–12:30

    Discussion, moderated by Barry Pizer, Alder Hey

  6. 12:30–13:30

    Lunch

  7. 13:30–14:00

    KeynoteCerebellar modulation of cognition: implications for cognitive development

    Catherine Stoodley, American University

  8. 14:00–14:30

    KeynoteThe nosology of pediatric post-operative cerebellar mutism syndrome: history and future directions

    Karin Walsh, Children's National Hospital

Radiology session, dedicated to Zoltán Patay

Chairs: Shivaram Avula, Alder Hey, and Rob Dineen, University of Nottingham

  1. 14:30–15:00

    KeynoteSolving the jigsaw: an update on the imaging of paediatric cerebellar mutism syndrome

    Shivaram Avula, Alder Hey

  2. 15:00–15:20

    Prediction. The Nottingham Workshop for CMS Prediction: outcome, reflections and next steps

    Rob Dineen, University of Nottingham

  3. 15:20–16:00

    Abstract presentations

    • Cerebellar-PAG "survival circuits" and the core symptoms of cerebellar mutism syndrome (CMS)

      Stu McAfee

    • Advanced MRI in medulloblastoma patients with and without CMS during treatment and follow-up

      Raja Khan

    • Neurological manifestations of postoperative cerebellar mutism syndrome in pediatric patients with medulloblastoma are strongly associated with disruption of the dentato-thalamo-cortical pathway: a diffusion tractography study

      Qing Ji

    • Predicting cerebellar mutism syndrome using lesion-symptom mapping

      Sebastian Toescu

  4. 16:00–16:30

    Tea and coffee break

  5. 16:30–17:00

    Discussion, moderated by Shivaram Avula and Rob Dineen

Scoring session

Chairs: David Walker, University of Nottingham, and Andrew Lux, University Hospitals Bristol

  1. 17:00–17:15

    The diagnosis of postoperative cerebellar mutism syndrome

    Coriene Catsman-Berrevoets, Erasmus MC Sophia Children's Hospital

  2. 17:15–17:30

    Measuring post-operative pediatric cerebellar mutism syndrome/posterior fossa syndrome: is there a one size fits all approach?

    Darcy Raches, St. Jude Children's Research Hospital

  3. 17:30–17:40

    Abstract presentation

    • Acute neuropsychological predictors of long-term language abilities in children with post-surgical CMS/CCAS

      Annet Kingma

  4. 17:40–18:10

    Discussion, moderated by David Walker and Andrew Lux

  1. 18:30–20:00

    Welcome drinks reception

Saturday 10 September 2022

Large-scale studies

Chairs: Barry Pizer, Alder Hey; Astrid Sehested, University of Copenhagen; and Giles Robinson, St. Jude Children's Research Hospital

  1. 08:30–09:00

    SJMB12

    Giles Robinson, St. Jude Children's Research Hospital

  2. 09:00–09:30

    Nordic-European Study

    Astrid Sehested, Aske Foldbjerg Laustsen and Jonathan Grønbæk, Rigshospitalet, Copenhagen University Hospital

  3. 09:30–09:45

    FASTigial Study

    Marita Partanen, Princess Máxima Center for Pediatric Oncology

  4. 09:45–10:15

    Discussion, moderated by Barry Pizer, Astrid Sehested and Giles Robinson

  1. 10:15–10:45

    Tea and coffee break

Surgery session

Chairs: Conor Mallucci, Alder Hey Hospital, and Jeff Wisoff, Hassenfeld Children's Hospital, NYU Langone Health

  1. 10:45–11:00

    CMS, looking back: mutism and pseudobulbar palsy in 1984. Origins of the posterior fossa syndrome

    Jeff Wisoff, Hassenfeld Children's Hospital, NYU Langone Health

  2. 11:00–11:30

    KeynoteWhere are we today with cerebellar mutism syndrome: has anything changed?

    Robert Keating, Children's National Hospital

  3. 11:30–12:30

    Abstract presentations

    • Cerebellar mutism syndrome (CMS) following posterior fossa surgery in children below 18 years: what we have learnt over the last 10 years

      Stephanie Schmidt

    • Feasibility of cerebello-cortical stimulation for intraoperative neurophysiological monitoring of cerebellar mutism

      Davide Giampiccolo

    • National multicentered retrospective review of clinical and intraoperative features associated with the development of cerebellar mutism after pediatric posterior fossa tumour resection

      Michelle Kameda-Smith

    • Application of the Rotterdam post-operative cerebellar mutism syndrome prediction model to patients operated for medulloblastoma in a single institution

      Raja Khan

    • SIOPE-MB6: integration of a randomized surgical question into a pan-European prospective clinical trial protocol for standard risk medulloblastoma

      Martin Mynarek

  4. 12:30–13:00

    Discussion, moderated by Conor Mallucci, Jeff Wisoff and Robert Keating

  1. 13:00–13:45

    Lunch

CCAS session

Chairs: Jeremy Schmahmann, Massachusetts General Hospital, and Coriene Catsman-Berrevoets, Erasmus MC Sophia Children's Hospital

  1. 13:45–14:15

    KeynoteThe cerebellar cognitive affective syndrome: implications and future directions

    Jeremy Schmahmann, Massachusetts General Hospital

  2. 14:15–14:25

    Abstract presentation

    • Evaluating the diagnostic validity of the cerebellar cognitive affective syndrome (CCAS) in pediatric posterior fossa tumour patients

      Andreas Peyrl

  3. 14:25–14:50

    Discussion, moderated by Jeremy Schmahmann

Speech therapy session

Chairs: Laura Hinkes Molinaro, Ann & Robert H. Lurie Children's Hospital of Chicago, and Sam Wright, Alder Hey Hospital

  1. 14:50–15:20

    Team approach for education and support of postoperative pediatric cerebellar mutism syndrome in the preoperative and immediately postoperative phase

    Laura Hinkes Molinaro, Ann & Robert H. Lurie Children's Hospital of Chicago

  2. 15:20–15:40

    Afternoon break

  3. 15:40–16:10

    Abstract presentations

    • OralVerbal fluency as a window to language processing changes in children with post-operative CMS/CCAS

      Kim Vos

    • OralCharacterising the spontaneous language outcomes in people who underwent cerebellar tumour surgery: differential outcomes in participants who did and did not experience postoperative cerebellar mutism

      Cheyenne Svaldi

    • FlashPost-operative paediatric cerebellar mutism syndrome: a national audit of speech and language therapy intervention

      Kirsty Maddock

    • FlashLanguage outcomes in children who underwent surgery for a posterior fossa tumour: a systematic review of the literature

      Cheyenne Svaldi

  4. 16:10–16:40

    Discussion, moderated by Laura Hinkes Molinaro and Sam Wright

Motor and ataxia session

Chairs: Helen Hartley, Alder Hey Hospital, and Deborah Sival, Beatrix Children's Hospital

  1. 16:40–17:10

    The rating of ataxia in young children

    Deborah Sival, Beatrix Children's Hospital

  2. 17:10–17:30

    Physical rehabilitation

    Helen Hartley, Alder Hey

  3. 17:30–18:00

    Discussion, moderated by Helen Hartley and Deborah Sival

  1. 19:00–23:00

    Conference social event: Ferry Cross the Mersey

Sunday 11 September 2022

  1. 08:30–09:00

    Business meeting of the Posterior Fossa Society

    Karin Walsh

Neuropsychology session

Chairs: Karin Walsh, Children's National Hospital, and Darcy Raches, St. Jude Children's Research Hospital

  1. 09:00–09:30

    Neuropsychology: posterior fossa syndrome and long-term neuropsychological effects

    Don Mabbott, SickKids Research Institute

  2. 09:30–09:50

    Neurocognitive trajectory in pediatric CMS

    Karin Walsh, Children's National Hospital

  3. 09:50–10:05

    Abstract presentations

    • OralNeurocognitive outcome, academic achievement and occupation in a consecutive sample of pediatric cerebellar tumor long-term survivors

      Andreas Peyrl

    • FlashA 4-year neurocognitive follow-up of children with a posterior fossa tumor

      Kristien Bullens

  4. 10:05–10:30

    Discussion, moderated by Karin Walsh and Darcy Raches

  1. 10:30–11:00

    Tea and coffee break

Rehabilitation session

Chair: Sharyl Samargia-Grivette, University of Minnesota Duluth

  1. 11:00–11:30

    REACH study findings across disciplines

    Sharyl Samargia-Grivette, University of Minnesota Duluth

  2. 11:30–11:40

    Abstract presentation

    • Sociocultural variables have a major impact on participation in patients treated for pediatric posterior fossa tumors

      Andreas Peyrl

  3. 11:40–12:00

    Discussion

  1. 12:00–13:00

    General discussion and closing remarks

    Karin Walsh, Robert Keating, Barry Pizer, Shivaram Avula, Jeremy Schmahmann, Sharyl Samargia-Grivette and Helen Hartley